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主讲人：Fu bingmei（美国纽约城市大学生物医学工程系）

题 目：Endothelial Surface Glycocalyx and Its Roles in Vascular Function

时 间：2015-6-12（星期五） 15：00~17：00

地 点：武汉大学新普京澳门娱乐场app网站学术报告厅（新9教三楼）

举办单位：武汉大学新普京澳门娱乐场app网站

欢迎广大师生参加！

摘要：On the luminal surface of our blood vessel walls, there is a coating called endothelial surface glycocalyx (ESG). The ESG plays important roles in vascular functions such as maintaining normal vascular wall permeability, forming a barrier between circulating cells (leukocytes and tumor cells) and vessel walls, as well as serving as a mechano-sensor for blood flows. Reduction of ESG has been reported in many vascular diseases including atherosclerosis, inflammation, myocardial edema, and diabetes. This talk will introduce ESG, and demonstrate how it plays aforementioned roles and how it is maintained.

个人简历：Dr. Bingmei Fu received her B.S., M.Eng. from the Department of Modern Mechanics of the University of Science and Technology of China in 1985 and 1988, respectively. Then she worked as an assistant professor for one year in Southwest Jiaotong University before she came to the U.S. in 1989. She had been working with Dr. Sheldon Weinbaum to develop transport models for the inter-endothelial cleft and obtained a Ph.D. in Mechanical Engineering from the City University of New York in 1995. After working with Dr. Roy Curry on in vivo single microvessel permeability for three years as a NIH postdoctoral fellow in the School of Medicine, University of California, Davis, she joined the Department of Mechanical Engineering at the University of Nevada, Las Vegas in 1998 as an assistant professor and was promoted to a tenured associate professor in early 2004. She moved to the Department of Biomedical Engineering of the City College of the City University of New York in the fall of 2004 and was promoted to a full professor in 2010. She was elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE) in 2012 and to the council of the World Association of Chinese Biomedical Engineers recently. She has been the reviewer for over 50 journals including Nature-methods, Scientific Reports, Biophysical Journal and Cancer Research. She is also the proposal reviewer for NIH, NSF, USAMRMC of the U.S., and discover grants of NSERCC of Canada.

Dr. Fu's major research activities involve modeling nano and micro transport phenomena in the microcirculation such as in transvascular, transcellular and transinterstitial processes, in vivo animal studies on understanding structural mechanisms of microvessel permeability related diseases and developing drug delivery strategies to the brain through the blood-brain barrier and the cerebrospinal fluid. These research projects have been supported by the NIH, NSF and Andrew Grove Foundation, which includes a NSF CAREER award.

个人主页：http://bme.ccny.cuny.edu/people/faculty/bfu